Notes
Antibacterial screening notes, from the bench side of the read-out
Working notes on the parts of antibacterial screening that are easy to get slightly wrong. Written for people who will be at a bench or a program review later the same week.
MultiCASE CASE Ultra pricing and license cost from 7 federal awards
MultiCASE publishes no price for CASE Ultra. Seven federal awards show what the FDA pays for CASE Ultra and META Ultra, how one flat rate held for seven years, and how it compares with Derek Nexus and Leadscope.
Read the note- Published
- 6 October 2026
- Read time
- 7 min
- Topic
- Buying
- Reference page
- Leadscope pricing
Every note links to the reference page that covers the same subject in full, and to the screen.
5 Oct 2026
Buying
Derek Nexus pricing and Lhasa Limited license cost from 32 federal awards
Lhasa Limited publishes no price for Derek Nexus. Thirty two federal awards show what a five user site license, the ICH M7 pair with Sarah Nexus and the full Knowledge Suite actually cost.
29 Sep 2026
Buying
Cresset Flare pricing and Flare software license cost, from 7 federal awards
Cresset publishes no commercial price for Flare. Seven federal awards show what a five user Flare Designer group, a Spark license and a Flare FEP GPU bundle actually cost.
28 Sep 2026
Buying
NONMEM license cost and NONMEM software pricing, from 12 FDA awards to ICON
ICON publishes no price for NONMEM. Twelve FDA awards show what the license actually costs, how rarely it moved, and what else a population PK stack needs.
27 Sep 2026
Buying
Simcyp Simulator price for a Certara Simcyp license as shown in 19 federal awards
Certara publishes no price for the Simcyp Simulator. Nineteen federal awards show what a node license, a departmental license and an institutional agreement actually cost.
26 Sep 2026
Buying
Chemaxon pricing for JChem, Marvin and Instant JChem licenses as shown in 38 federal awards
Chemaxon publishes no commercial price, before or after Certara. Thirty eight federal awards show what JChem, Marvin and Instant JChem actually cost, per user and per year.
25 Sep 2026
Buying
Pipeline Pilot pricing and what BIOVIA Pipeline Pilot costs in the public award record
BIOVIA publishes no price for Pipeline Pilot, and the per-user figures online cite nothing. Federal awards show what the server, the clients and the collections actually cost.
22 Sep 2026
Buying
BIOVIA Discovery Studio price for a license and what the free Visualizer leaves out
Dassault publishes no price for Discovery Studio, and the free Visualizer confuses the question further. Public award records put real numbers on both ends of the range.
21 Sep 2026
Buying
StarDrop pricing per year from Optibrium and what moves the number
Optibrium publishes a range where almost nobody else publishes anything: from about $10,000 a year into six figures. Here is what sits behind that spread, module by module.
17 Sep 2026
Buying
Schrodinger software cost per license and why nobody publishes the number
Schrodinger publishes no price, and the figure everyone quotes is academic, historical and absent from the live listing. Here is how the licensing actually works and what to budget against.
16 Sep 2026
Buying
Best antibacterial compound libraries for screening, and what each one actually gives you
Four vendors sell a ready-made antibacterial deck and they are two different products. Here is what each contains, which one fits a Gram-negative program, and what the quote hides.
15 Sep 2026
Buying
Antibacterial screening software pricing and the real cost per compound screened
Almost nobody in this category publishes a price, which makes budgeting a screening cascade harder than it should be. Here is the arithmetic, and what actually moves the number.
10 Sep 2026
Buying
Best antimicrobial peptide design software for a preclinical peptide program
The AMP toolchain splits into four jobs and most teams buy two tools that do the same one. Here is what each category actually returns, and which gap costs the most.
9 Sep 2026
Buying
Best antibacterial screening software for a small biotech discovery team
Most of the tools sold into discovery store your data or model your target. Very few answer the question an antibacterial program actually asks, which is compound against strain.
4 Aug 2026
Chemistry
Lead optimization in drug discovery, when the target is a bacterium
Standard lead optimization pushes lipophilicity up. For Gram-negatives that is often exactly the wrong direction, and the series dies on the plate.
28 Jul 2026
Screening
High content screening and when an image beats a growth curve
A growth curve tells you whether a compound worked. An image can tell you how, which is the more expensive question to answer later.
21 Jul 2026
Method
MIC in microbiology and how the number is actually measured
Broth microdilution, agar dilution and gradient strips give different answers for good reasons. Here is what happens on the bench, and where the error comes from.
14 Jul 2026
Method
Minimum inhibitory concentration definition and what a MIC actually tells you
The MIC is the lowest concentration that stops visible growth. That sentence hides a plate, a dilution series and a set of conventions worth knowing.
Reference pages
Longer, more structured background on the same subjects.
Reading is slower than running one screen
The screen on the homepage takes about ten seconds and returns a matrix for six strains. Start there, then come back for the detail.
What you are agreeing to
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